Sialic acid acetylesterase
WebMay 6, 2010 · Heterozygous loss-of-function germline rare variants and a homozygous defective polymorphic variant of SIAE were identified and represent a strong genetic link to susceptibility in relatively common human autoimmune disorders. Sialic acid acetylesterase (SIAE) is an enzyme that negatively regulates B lymphocyte antigen receptor signalling … WebJun 16, 2010 · Sialic acid acetylesterase (SIAE) is an enzyme that negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of …
Sialic acid acetylesterase
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WebRecombinant Human Sialate O-Acetylesterase is produced by our Mammalian expression system and the target gene encoding Ile24-Lys523 is expressed with a 6His tag at the C ... WebMar 3, 2024 · The sialic acid concentration in culture supernatants was consistent with the growth profiles of pneumococcal strains. ... Rott R, Klenk HD, Muller HP, Shukla AK, …
WebSialate 9 (4)-O-acetylesterases (EC 3.1.1.53) have been isolated from equine liver, bovine brain and influenza C virus. In this latter case, the esterase represents the receptor … WebSialic acid acetylesterase (SIAE) removes 9-O-acetyl moieties from acetylated sialic acids. The B cell receptor (BCR) inhibitory receptor CD22 cannot bind 9-O-acetylated !2-6-linked …
WebDistribution of Sialic Acid 0-Acetylesterase in Rat Liver Tissues-Extracts from several tissues of adult male Sprague- Dawley rats were assayed for sialic acid 9-0 … WebNov 1, 2024 · Sialic acids are a family of nine carbon keto-aldononulosonic acids presented at the terminal ends of glycans on cellular membranes. α-Linked ... C. NeuA O-acetylesterase activity is specific ...
WebOct 20, 2014 · Nucleic Acids Research Sep 2012 ... Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic …
WebMar 29, 2024 · Ursini G, Punzi G, Langworthy BW, Chen Q, Xia K, Cornea EA, Goldman BD, Styner MA, Knickmeyer RC, Gilmore JH, Weinberger DR. Placental genomic risk scores … tsf60arThe enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction ... "High performance liquid chromatography of enzymes of sialic acid metabolism". Hoppe-Seyler's Z. Physiol. Chem. 363: 1039–1040. This page was last edited on 16 August 2024, at 15:45 (UTC). Text is available under the Creative … See more The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate In human it is encoded by the SIAE gene located on See more The SIAE gene contains 15 exons and expresses a protein that is approximately 56 kDa in size. It is known to be expressed in the adult See more SIAE activity negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance. It down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for See more Genetic defects in SIAE have been associated with multiple autoimmune diseases. Loss of function mutations in SIAE are much more frequently found in humans with See more philodendron scandens flowersWebOct 1, 2024 · Sialic acid acetylesterase (SIAE) removes acetyl moieties from the carbon 9 and 4 hydroxyl groups of sialic acid and recently a debate has been opened on its … philodendron serpens chocolateWebAug 24, 2010 · Sialic acids are acidic 9-carbon sugars typically found at the nonreducing end of sugar chains. They are frequently modified by 9-O-acetylation, and this modification is … philodendron satin pothosWebMay 28, 2015 · sialic acid-specific 9-O-acetylesterase and RNA expression in cells of hematopoietic and non-hematopoietic origin. Nucleic acids research, 24:4003-4008. … tsf61a-h 取説philodendron selloum temperatureWebSialic acids (Sias) are carbohydrates that usually occupy the terminal positions in longer carbohydrate chains, ... The Hemagglutinin-Esterase of Mouse Hepatitis Virus Strain S is a … philodendron scandens common name