Poly rc -binding protein 1

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August undefined, 2024

WebSep 10, 2009 · POLY(rC)-BINDING PROTEIN 1; PCBP1 HGNC Approved Gene Symbol: PCBP1 (from NCBI) TEXT. Cloning and Expression. Leffers et al. (1995) described the cloning and characterization of 2 cDNAs for poly(rC)-binding proteins, called PCBP1 and PCBP2 (601210) by them. The authors analyzed an EST database for sequences that … WebFeb 28, 2024 · The hepatitis C virus (HCV) co-opts a number of cellular elements – including proteins, lipids, and microRNAs – to complete its viral life cycle. The cellular RNA-binding protein poly(rC)-binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5’ untranslated region (UTR), but its importance in the viral life cycle has …

Poly(rC) binding protein 2 (PCBP2) promotes the viability of …

WebThe hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding protein, poly(rC)-binding protein 1 (PCBP1), was previously reported to bind to the 5′ untranslated region (UTR) of the HCV genome; however, its importance in the viral life cycle has remained … Web1997)+ Poly(rC) binding proteins 1 and 2 form a UV-light induced covalent bond with nt 24 of the 59-terminal cloverleaf of poliovirus RNA (Andino et al+, 1993)+ In a second ribonucleoprotein complex, both poly(rC) bind-ing protein(s) and viral protein 3CD bind to the 59-terminal cloverleaf structure (Gamarnik &Andino,1997; flashcard maker for pc

Poly(rC) binding proteins mediate poliovirus mRNA stability.

WebA protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A. 1977 Jan; 74 (1):59–63. [PMC free article] [Google Scholar] Leffers H, Dejgaard K, Celis JE. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem. 1995 Jun 1; 230 (2):447–453. WebPoly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in mammalian cells. … WebJan 29, 2024 · The hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding … flash card maker online free

PCBP1 poly(rC) binding protein 1 [ Homo sapiens (human) ]

PCBP1 - Wikipedia

WebAug 21, 2024 · However, splicing factors can also play negative roles in tumorigenesis. In the current review, we focus on splicing factor poly(rC)-binding protein 1 (PCBP1), a novel tumor suppressor that is characterized by downregulation in many cancer types and shows inhibition of tumor formation and metastasis. WebJan 20, 2024 · We found a C-rich element (CRE) in mu-opioid receptor (MOR) 3'-untranslated region (UTR) to which poly (rC) binding protein 1 (PCBP1) binds, resulting in MOR mRNA … flashcard maker quizletWebPoly(rC) binding protein 1 (PCBP1) is … Coxsackievirus B3 (CVB3) is a positive single-strand RNA virus causing myocarditis, pancreatitis and meningitis. During CVB3 infection, … flash card maker free word

"WebSep 1, 2024 · Poly(rC) binding protein 1 (PCBP1) is a direct target of miR-21. • PCBP1 benefits CVB3 replication via blocking the translation of p62/SQSTM1. • Expression of PCBP1 is reduced by upregulated miR-21 upon CVB3 … " - Poly rc -binding protein 1

Poly rc -binding protein 1

WebMay 21, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in … WebDec 8, 2024 · The iron chaperone and nucleic acid-binding activities of poly (rC)-binding protein 1 are separable and independently essential. RNA-Binding Proteins PCBP1 and …

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WebOct 15, 2024 · Poly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a relative molecular weight of 38 kDa, which is characterized by downregulation in many … WebMay 1, 2024 · Poly(rC)-binding protein 1 (PCBP1) is a multifunctional RNA-binding protein that plays various roles in gene transcription, RNA regulation, and iron chaperone [8, 9]. PCBP1 is a major iron chaperon facilitating iron loading to ferritins and an RNA-binding protein interacting with other target protein BolA2 independently at its different faces [10].

WebPoly(rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized by its ability to interact with poly(C) with high affinity in a sequence-specific manner. PCBP2 … WebCommon to processing body (P body) and stress granule. K12889 PCBP1; poly (rC)-binding protein 1. Spliceosome [BR: ko03041] Common components. Common spliceosomal components. hnRNP proteins. K12889 PCBP1; poly (rC)-binding protein 1. BRITE hierarchy.

WebSep 11, 2003 · Here, we show that members of the poly (rC) binding protein family, poly (rC) binding protein 1 (PCBP1), poly (rC) binding protein 2 (PCBP2) and hnRNPK were able to activate the IRES in vitro up ... WebMay 11, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the …

WebJul 1, 2024 · Poly(rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized by its ability to interact with poly(C) with high affinity in a sequence-specific manner. PCBP2 contains three K homology domains, which are consensus RNA-binding domains that play a role in recognizing and combining with RNA and DNA.

WebMay 1, 2024 · Poly(rC)-binding protein 1 (PCBP1) is a multifunctional RNA-binding protein that plays various roles in gene transcription, RNA regulation, and iron chaperone [8, 9]. … flash card machinesWebPoly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a rela-tive molecular weight of 38 kDa, which is characterized by downregulation in many cancer … flashcard maker pdfWebMay 21, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in mammalian cells. Although PCBP1 distributes iron in cells, its role in managing iron in mammalian tissues remains open for study. flashcard maker app iphoneWebMay 11, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several oncogenic genes. ... Poly(rC) binding protein 1 represses the translation of STAT3 through 5' UTR. @article{Li2024PolyrCBP, title={Poly ... flashcard maker printWebMay 10, 2024 · Objective To monitor the phosphorylation modifications and cellular localization of poly(rC)-binding protein-1 (PCBP1) during the cell cycle progression of Hela cells. Result Hela cells highly synchronized at five different phases from interphase to mitosis were obtained. Using mitotic phosphoprotein-specific monoclonal antibody MPM … flash card maker printable freeWebSep 1, 2024 · Poly(rC) binding protein 1 (PCBP1) is a direct target of miR-21. • PCBP1 benefits CVB3 replication via blocking the translation of p62/SQSTM1. • Expression of … flashcard maker softwareWebPoly(rC)-binding protein 1 1 publication. Alternative names. Alpha-CP1 1 publication. Heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) Nucleic acid-binding protein … flashcard maker download