Platinum and taxane

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August undefined, 2024

WebbTaxane, platinum and 5-FU prior to chemoradiotherapy benefits patients with stage IV neck node-positive head and neck cancer and a good performance status J Cancer Res Clin … WebbThe objective of the present work was to evaluate the effectiveness of methods used to prevent and treat hypersensitivity reactions to platinum- or taxane-based chemotherapy …

Chemotherapy for Ovarian Cancer Intraperitoneal Chemotherapy

Webb12 apr. 2024 · Cervical Cancer; New and exciting data continue to emerge in the management of patients with cervical cancer. To that end, the European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology/European Society of Pathology (ESGO/ESTRO/ESP) groups have come together to deliver a … Webb12 juli 2024 · Selection criteria: We included randomised controlled trials of taxane monotherapy for adult women diagnosed with recurrent epithelial ovarian, tubal or … portable outdoor full bar

Platinum-Based Chemotherapy: Uses, Effectiveness, Side Effects

Webb6 dec. 2024 · Abstract and Figures Platinum (Pt) derivatives such as cisplatin and carboplatin are the class of drugs with proven activity against triple-negative breast cancer (TNBC). This is due to the... Webb6 dec. 2024 · Platinum (Pt) derivatives such as cisplatin and carboplatin are the class of drugs with proven activity against triple-negative breast cancer (TNBC). This is due to … WebbUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol ®) or docetaxel (Taxotere ® ). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks. portable outdoor electric water heater

Platinum and Taxane Based Adjuvant and Neoadjuvant Chemotherapy in …

Novel Roles for Platinum and Taxane Agent Skin Testing in Risk ...

WebbOvarian cancer is one of the most common malignant tumors in gynecology with a high incidence. Combination therapy, eg, administration of paclitaxel followed by a platinum anticancer drug is recommended to treat ovarian cancer due to its advantages in, eg, reducing side effects and reversing (multi)drug-resistance compared to single treatment. Webb21 sep. 2016 · The cellular toxicity of taxanes and platinum agents are likely controlled by the actions of multiple genes. 8 - 10 Genes involved in transport (eg, ABCB1, ABCC1, and ABCC2 ), metabolism (cytochrome P450s), and pharmacodynamics (eg, TP53, CDKN1A) all appear to play a role in taxane efficacy. 9 Similarly, platinum agents such as carboplatin … irs behind in processing 2020 returnsWebbThis translational study aims to evaluate the potential role of rs1042713 in the beta 2-adrenergic receptor (ADRB2) gene in predicting pathological complete responses (pCRs) to taxane- and platinum-based neoadjuvant chemotherapy in locally advanced breast cancer (LABC).Materials and methods: The distribution frequencies of rs1042713 were … irs behind in processing refunds 2021

"WebbCEF-T indicates fluorouracil, epirubicin, and cyclophosphamide followed by docetaxel; HR, hazard ratio; HRR, homologous recombination repair; and PCb, paclitaxel and carboplatin. Table 1. Patient Characteristics by Treatment Group View LargeDownload Table 2. First Disease-Free Survival Event by Treatment View LargeDownload Supplement 1. " - Platinum and taxane

Platinum and taxane

OncoMed Highlights New Data Presented at the American …

Webb1 jan. 2015 · Background In platinum-taxane resistant epithelial ovarian cancer (EOC), we aimed to determine the effectiveness. Patients and Methods Between 2004 and 2013, patients afflicted with platinum-taxane resistant EOC and who were administered a 30-minute i.v. infusion of single-agent gemcitabine at a dose of 1,250 mg/m2 on the 1st, 8th … WebbBackground: Chemotherapy with taxanes and platinum compounds has resulted in substantial survival benefits both in adjuvant and metastatic settings. However, as a side …

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WebbOvarian cancer is one of the most common types of solid carcinoma diagnosed during pregnancy. Taxane plus a platinum derivative is a combination therapy that is … WebbAbstract. One of the most neglected aspects of chemotherapy are changes, and possible consequences of these changes, that occur in normal somatic cells. In this review, we …

WebbFör 1 dag sedan · Terence Friedlander, MD, discusses the significance of the FDA approval of enfortumab vedotin combined with pembrolizumab for patients with locally advanced or metastatic urothelial carcinoma, and ... WebbHigh-grade serous carcinoma (HGSC) of the ovary is predominantly diagnosed at late stages and primarily treated with debulking surgery followed by platinum/taxane-based chemotherapy. Although certain patients benefit significantly from currently used chemotherapy, there are patients who either do not respond or have an inadequate …

WebbBoth anthracyclines and taxanes are classic therapeutic agents for breast cancer, which are extensively utilized in treating all subtypes of breast cancer including TNBC. 6 In fact, most patients with TNBC were anthracyclines- and taxanes-pretreated, while treating patients who failed to these 2 agents is usually difficult because medication … Webb21 dec. 2024 · Platinum (Pt)-based chemo-regimens have been proved effective in neoadjuvant and salvage chemotherapy of triple negative breast cancer (TNBC). However, the survival benefit of Pt-based regimens...

Webbmanaging platinum and taxane agent HSRs, continued im-provements can be made to reﬁne existing risk stratiﬁcation strategies for patients with platinum and taxane HSRs. TABLE I. Four-step reintroduction protocols reported for carboplatin1,7-9 Step Pradelli et al1 Takase et al7 Altwerger et al8 Li et al9 1 1:1000 1:1000 1:1000 1:1

Webb5 apr. 2024 · Following treatment with tarextumab and platinum-based chemotherapy, ... Anti-RSPO3 plus taxane treatment significantly reduced the number of tumor initiating cells. portable outdoor heaters at lowe\u0027sWebbPredicting toxicity of platinum and taxane-based chemotherapy in older patients with gynecologic cancer. Our study confirmed that the CARG toxicity tool could predict … irs behind in processing returnsWebbför 9 timmar sedan · Professor Steven W. Cheung of otolaryngology at the institution stated that while hearing loss linked to the administration of platinum drugs had been reported in patients with head and neck as well as testicular cancers, the study was the first to show that tinnitus and hearing loss were common issues for adult survivors of … portable outdoor heaters walmartWebb13 apr. 2024 · Combination therapy with the novel agent BXCL701 and pembrolizumab showed strong clinical activity in in patients with platinum-resistant small cell neuroendocrine carcinoma metastatic castration-resistant ... and 50% had prior taxane chemotherapy. The median duration of follow-up was 30.8 weeks (range, 1.9-86.9), and … portable outdoor led video infield displaysWebb10 apr. 2024 · To determine the therapeutic drugs associated with ring enhancement, which individual drugs in the regimens were administered during the intervals between the two MRI examinations was investigated as follows: AC, Taxane, HER2-targeted agent (trastuzumab, pertuzumab), and platinum agent. irs behind in refundsWebb13 apr. 2024 · In patients with programmed death-ligand 1 (PD-L1)-negative aTNBC, single-agent or combination chemotherapy represents the standard-of-care, first-line therapy. 2 By contrast, in patients with PD-L1-positive aTNBC, which represent about 30–40% of all aTNBC cases, the combination of taxane- or carboplatin–gemcitabine chemotherapy … irs behind in processing tax returnsWebbWe will discuss the current status of FAK inhibitors in ovarian cancers, their therapeutic competencies and limitations, and further propose that the combination of FAK … portable outdoor heaters rent