Phenanthrene metabolism

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August undefined, 2024

WebA monooxygenase which catalyzed the oxidation of 1-hydroxy-2-naphthoateto 1,2-dihydroxynaphthalene was purified from the phenanthrene- and naphthalene-degrading Pseudomonas putida strain BS202-P1. The purified protein had a molecular weight of45 kDa and required NAD (P)H and FAD as cofactors. WebPhenanthrene (Phe), a hazardous chemical, is widely found in air, soil, ... Activation of the xenobiotic metabolism and oxidative stress response by mixtures of organic pollutants extracted with in-tissue passive sampling from liver, kidney, brain and …

Phenanthrene Metabolism in Smokers: Use of a Two-Step …

WebMar 1, 2007 · Phenanthrene metabolites were analyzed using GC–MS and LC–MS. The cultures were adjusted to pH 2 with 2 M HCl, and were extracted twice using equal volume of ethyl acetate [3]. The extracts were combined, dried with anhydrous Na 2 SO 4, and rota-evaporated at 35 °C. The extraction residues were dissolved in methanol. WebMar 20, 2024 · Here, the co-metabolism of phenanthrene (PHE) and Fe(III) by marine-derived Kocuria oceani FXJ8.057 was realized under aerobic condition. In the presence of both PHE and Fe(III), the rates of PHE degradation and Fe(III) reduction by K. oceani FXJ8.057 were synchronously enhanced, likely because the strain secreted riboflavin, which acted as an ... chevy dealer huntington ny

Phytoremediation for phenanthrene and pyrene contaminated soils

WebThe metabolism of phenanthrene, a polycyclic aromatic hydrocarbon (PAH), by Streptomyces flavovirens was investigated. When grown for 72 h in tryptone yeast extract broth saturated with phenanthrene, the actinomycete oxidized 21.3% of the hydrocarbon at the K-region to form trans-9,10-dihydroxy-9,10-dihydrophenanthrene (phenanthrene trans … WebMetabolism. Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase is an enzyme that uses (+)-cis-3,4-dihydrophenanthrene-3,4-diol and NAD+ to produce phenanthrene-3,4-diol, … WebPseudomonas sp. strain PPD can metabolize phenanthrene as the sole source of carbon and energy via the 'phthalic acid' route. The key enzyme, 1-hydroxy-2-naphthoic acid dioxygenase (1-HNDO, EC... chevy dealer humble tx

A phenanthrene-degrading strain - ScienceDirect

Insights from comparative proteomic analysis into degradation of ...

WebPhytoremediation of soil contaminated with phenanthrene and pyrene was investigated using twelve plant species. Plant uptake and accumulation of these chemicals were evaluated. At the end of the experiment(45 d), the remaining respective concentrations of soil phenanthrene and pyrene in spiked veget … WebMicrobial co-metabolism is crucial for the efficient biodegradation of polycyclic aromatic hydrocarbons (PAHs); however, their intrinsic mechanisms remain unclear. ... Moreover, three-ring PAHs with different structures (e.g. phenanthrene, anthracene, and fluorene) are frequently considered model pollutants for analysing the biodegradation of ... good water animal hospital georgetownWebOct 11, 2006 · Phenanthrene is the simplest PAH with a bay region, a feature closely associated with carcinogenicity. The urinary metabolite r -1, t -2,3, c -4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene (PheT) is a measure of metabolic activation, whereas phenanthrols (HOPhe) are a measure of detoxification. goodwater alabama police chief

"WebDec 1, 2010 · This is the first report of the complete degradation of a polycyclic aromatic hydrocarbon molecule by Gram-negative Ochrobactrum sp. describing the involvement of the meta -cleavage pathway of 2-hydroxy-1-naphthoic acid in phenanthrene assimilation. Ochrobactrum, phenantherene, 2-hydroxy-1-naphthoic acid, meta -cleavage, biodegradation " - Phenanthrene metabolism

Phenanthrene metabolism

The hepatoprotective effects of Herbt Tea Essences on phenanthrene …

WebMar 21, 2024 · In this study, we identified natural pure compounds from two chemical classes, phenanthrenes and dihydrophenanthrenes, which directly activate AMPK through the ADaM-binding pocket. These compounds increase AMPK activity in intact cells and show dose-dependent inhibition of de novo lipogenesis in primary hepatocytes. WebNov 26, 2024 · The rate-limiting step reaction is the metabolism of phenanthrene to phenanthrene 3,4-dihydrodiol by RHD (Liang et al. 2024a, b). The RHD of strain AD-3 contains α subunit, β subunit, [2Fe-2S] type ferredoxin and glutathione reductase (GR), and is classified as a Type IVαβ RHD system (Kweon et al. 2008).

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WebJan 1, 2024 · Phenanthrene (Phe), among the most ubiquitous polycyclic aromatic hydrocarbons (PAHs) existing in nature and foodstuffs, has severe effects on hepatic … WebOct 1, 2012 · In route I, metabolism of phenanthrene was initiated by the dioxygenation at C‐3,4 via 1‐hydroxy‐2‐naphthoic acid, 1‐naphthol, salicylic acid and gentisic acid. In route II, phenanthrene was metabolized to 9‐phenanthrol and 9,10‐phenanthrenequinone. Further study indicated that strain AD‐3 exhibited a wide spectrum of substrate ...

WebNov 1, 2024 · After 3-day incubation, the active microbes involved in phenanthrene metabolism divided and eventually lost magnetism. By magnetic harvesting, they were separated from the inert microbes and remained in aqueous phase as magnetic-free cell (MFC) suspension. WebApr 1, 2024 · The strain showed good performance in the metabolism of phenanthrene. During the degradation, phenanthrene was broken down into five detected compounds: …

WebPhenanthrene metabolism in smokers : Use of a two-step diagnostic plot approach to identify subjects with extensive metabolic activation. / Wang, Jing; Zhong, Yan; Carmella, Steven G. et al. In: Journal of Pharmacology and Experimental Therapeutics, Vol. 342, No. 3, 09.2012, p. 750-760. Research output: Contribution to journal › Article ... WebAbstract The metabolism of phenanthrene by a gram-negative organism able to use this compound as a sole source of carbon and energy has been examined. 1-Hydroxy-2 …

WebPhenanthrene, a tricyclic PAH containing three fused benzene rings in angular arrangement, is a major constituent of coal derivatives and fossil fuels. Phenanthrene is one of the 16 PAHs in the list of priority pollutants compiled by the US Environment Protection Agency.3 This compound being en-countered regularly in environmental samples is

WebAlthough phenanthrene contains a bay region, it is not a human carcinogen. Similar to BaP, it is metabolized to phenols, dihydrodiols, and tetrols. It is likely that quantification of phenanthrene metabolites will enhance our understanding of human metabolism of … Igor P. Pogribny, in Encyclopedia of Cancer (Third Edition), 2024 Benzo[α]pyrene. … Morphine. We have shown that morphine and HIV-1 viral protein tat alone and in … Although diverse plant alkaloids are active as defensive compounds against … chevy dealer idaho fallsWebJan 19, 2024 · In this study, we investigated the roles of ryegrass in phenanthrene degradation in soils using DNA stable isotope probing (SIP) and metagenomics to reveal a potential explanation for conflicting results among phytoremediation studies. Phenanthrene biodegradation efficiency was improved by 8% after 14 days of cultivation. goodwater baptist church magee msWebFeb 4, 2024 · Representing over 50% of metagenomes detected, MAGs 001 and 002 appear to represent organisms closely linked to phenanthrene metabolism. Of these, only bin 002, which represents 30% of the ... chevy dealer huntley ilWebMar 21, 2024 · In this study, we identified natural pure compounds from two chemical classes, phenanthrenes and dihydrophenanthrenes, which directly activate AMPK through … goodwater alabama zip codeWebArthrobacter sp. P1-1, isolated from a polycyclic aromatic hydrocarbon (PAH)-contaminated site in Hilo, HI, USA, can decompose phenanthrene (40 mg l (-1)) completely within 7 days. A detailed phenanthrene metabolism map was constructed based on metabolite analysis and replacement cultures. chevy dealer in ada okWebJan 1, 2003 · Phenanthrene-metabolizing soil microbial communities were characterized by examining mineralization of [14C]phenanthrene, by most-probable-number (MPN) counting, by 16S-23S spacer DNA analysis of ... good water animal hospital georgetown txWebMar 9, 2016 · Co-metabolism 1-naphtholCo-metabolism strainGY2B MSMculture having 1-naphthol 1-hydroxy-2-naphthoic acid 25mg proceduredescribed above otheraromatic compounds test followed.2.6. Isolation phenanthrenemetabolites identifyintermediate products phenanthrenedegradation, micro-organism 100mg solecarbon energysource. chevy dealer in adams wi