WebDue to a lack of significant genetic variance in the superior backcross generation, epistasis was concluded to be of minor importance in the choice of segregating population to develop for selection of superior yielding lines;The F[subscript]2 population had significantly greater mean grain yield (0.27 Mg ha[superscript]-1) while significantly ... WebTesting the existence of quantitative trait locus (QTL) effects is an important task in QTL mapping studies. In this paper, we assume the phenotype distributions from a location-scale distribution family, and consider to test the QTL effects in both location and scale in the backcross studies with double recombination occurring.
Enhancing backcross programs through increased …
WebCross those males from the second backcross that carry your mutation or transgene to C57BL/6J females. Cross the males and females from this backcross together to get … WebGeneration Definitions. Mouse strain generation numbers provide additional information on the genetic background and breeding history of mouse strains that cannot be captured in the mouse strain names. The symbols and definitions for mouse generation numbers used by The Jackson Laboratory are listed below. N. N umber of backcross generations. fairground attraction album covers
How to Refresh Your Mutant or Transgenic Mouse Strains
WebApr 25, 2016 · Why backcrossing knockout mice? "The lysosomal acid lipase (lal) −/− mice were produced in these laboratories and genotyped as described [19]. These mice were … WebMar 9, 2024 · The success of a backcross program depends on two factors: the reduction of the linkage drag around the target locus and the recovery of the recurrent genome in … WebAug 18, 2016 · At the tenth backcross, approximately 99.9% of the genome is derived from the recipient strain. While traditional backcrossing is still used, this process can be accelerated via selecting breeders in each backcross generation which have the highest percentage of recipient genome. This is commonly called speed congenics. Congenic … fairground advert